Present Status of Microwave Ablation on Thyroid Nodules

In recent years, the detection rate of thyroid nodule is increasing year by year, and in random population, 40% of nodules can be detected by high-resolution ultrasonography; the incidence of thyroid cancer is also increasing, and it is one of the most rapidly increasing malignant tumors now.

At present, surgical removal remains the dominant concept, but with the change of diet structure and increase of life pressure, the patients with thyroid diseases tend to be younger. Patients are not only asking to cure the tumor, but also to keep the beauty of neck and not to affect normal life and work.

On the premise of the exact effect, the perfect minimally invasive tumor ablation technique can satisfy the requirements of less trauma, less complication and faster recovery, and achieve the effect of minimally invasive cosmetic surgery.

At the same time it does not affect the patients’ normal life. The treatment of thyroid tumor is developing rapidly in the direction of minimally invasive therapy. Among them. microwave ablation has the advantages of fast heating rate. strong ablation power, less influence by blood flow, large ablation range and stability, which has become one of the most promising therapeutic methods in the ablation field

Cooling Circulation Microwave Ablation (MWA)

Through microwave tissue thermocoagulation effect, the pathological tissue produces biological hyperthermia effect and it causes dehydration, coagulation, apoptosis and necrosis of nodule tissues.

€ Advantages of ECO Microwave Generator

  • CE, FDA approved 2.45GHz water cooling Microwave System;
  • Touch screen interface, easy to operate:
  • Multiple safety measures, ensures effectiveness & safety.
  • Special Designed Thyroid Ablation Mode;
  • Pulse Mode to minimize operational pain.

Incidence rate of benign breast tumors

Benign breast tumor is a common breast disease, more common in young women, the probability of developing into a malignant tumor is very small. However, benign tumors grow slowly, especially during pregnancy. Due to the changes of hormones in the body, a small number of benign tumors will grow rapidly or even become malignant. During the period of suffering from benign tumors, regular examinations are needed to monitor the growth of tumors.

Fibroadenomas is the most common benign tumor of breast, may cause change of shape and anxiety. Possibility of malignant transformation.

Local resection

Resection will be complete, but as with all surgical procedures, breast lump removal can carry some risks, including: infection, pain, swelling, scar tissue, change in appearance of the breast.

Vacuum assisted breast circumcision

Minimally invasive operation, scar is about 2mm, but the tissue damage inside the breast is not small, and for patients with multiple or larger nodules,repeated circumcision increases the risk of bleeding.

Thermal ablation MWA, RFA, Laser

Minimally invasive, less pain, shorter operation time, won’t affect appearance and function of mammary gland.

Principle of Microwave Ablation

Microwave ablation is a new type of minimally invasive treatment, which is carried out under real-time monitoring of ultrasound equipment. It uses an ablation antenna with a diameter of only 2mm to penetrate into the tumor through percutaneous approach. It can kill the tumor cells by generating high temperature inside the tumor, which can avoid the resection of the lesion tissue.

Indications – Benign Breast Nodules

  • Tumor size smaller than 3cm in greatest diameter confirmed by using US and CEUS;
  • Distance between nodule and the skin and ectopectoralisz 0.5 cm;
  • Nodule should not be located in the nipple areola area;
  • Patient requests for the treatment and has beauty needs.

Indications – Breast Fibroadenoma

  • B-RADS grade 3 or conventional ultrasound BI-RADS grade 4A and contrast-enhanced ultrasound or breast

  • MRI result indicates grade 3; for patients over 35 y/o, BI-RADS grade 3 or below;

  • The tumour smaller than 3cm in greatest diameter confirmed by using US and contrast-enhanced us (CEUS); • Fibroadenoma confirmed by core needle biopsy;

  • For multiple tumors, breast MRI evaluation can be considered, and the following conditions must be met:

  • (1) Longest diameter measured by ultrasound and contrast-enhanced ultrasound is 1-3 cm;
  • (2) Distance between tumor and skin/ectopectoralis > 0.5 cm;

Comparison of different treatment methods

Low frequency radio-waves

  • Stable treatment temperature

  • Only monitored by MRI

  • Limited usage for tumor subtypes

  • Low success ratio


  • Real noninvasive treatment

  • Less dissipation of heat

  • Tiny ablate target

  • Longer treatment time


Application scope is limited, focus area is small, needs to be repeated for many times More effective for smaller lesions with thinner abdominal wall and less blood supply Operation is time-consuming


  • Ice ball could be seen under MRI
  • Not good for larger size tumors (>2cm)
  • Several freeze-thaw cycles during treatment
  • Cryo-expense

Advantages of microwave ablation for Breast Tumor

  • Simple procedure, short operation time;

  • More safe and effective;

  • Minimally invasive “patient friendly”procedure,

  • Fast recovery with very short hospital stay:

  • Less complications;

  • Achieves cosmetic effect.

Incidence rate of benign uterine diseases


Fibroids are the most common benign tumors of the female genital tract, with a symptomatic occurrence rate of 20%-40% in reproductive-age women. Clinical symptoms: Abnormal uterine bleeding, secondary anemia, pelvic compression symptoms and pain, reproductive dysfunction, etc.


Most often diagnosed in middle-aged women and women who have had children. With the delayed childbearing age, the incidence rate among unfertile women has increased in recent years Clinical symptoms: Heavy or prolonged menstrual bleeding, severe cramping or sharp, knife like pelvic pain during menstruation (dysmenorrhea), chronic pelvic pain, etc.

Principle of microwave ablation

With the guidance of imaging system, microwave ablation antenna is directly punctured into the tumor. Polar molecules inside the tissue move rapidly within microwave electromagnetic field, generating heat through mutual friction. When the intra-tumor temperature reaches 60°C, the cancer cell proteins will be denatured and result in irreversible necrosis. This procedure will have very small effect on other tissues. It will help improve patient’s immunity and inhibit the proliferation of cancer cells.

Indications - Fibroids

  •  Clinically diagnosed fibroids. FIG grade 0-6
  • Accompanied by abdominal pain, menorrhagia, secondary anemia, compression and other symptoms
  • Patient has no perimenopausal signs

Advantages of microwave ablation in the treatment of fibroids and adenomyosis

  • Preserve uterus, no damage to pelvic structure. Lesions wil be inactivated and significantly reduced in size after ablation. which can improve or eliminate the clinical symptoms (such as dysmenorrhea, large menstrual volume, anemia, etc.).
  • Has no effect on ovarian function, menstrual cycle will be normal after ablation.
  • No surgery required, can be treated through percutaneous or transvaginal approach,
  •  Simple operation, short ablation time, less trauma, no scar,safe and effective.